Design, synthesis and evaluation of biological activities of some novel anti-TB agents with bio-reducible functional group

[Image: see text] Introduction: With regard to the anti-mycobacterial activity of 2-pyrazinoic acid esters (POEs), recent studies have shown that both pyrazine core and alkyl part of POE interact with the fatty acid synthase type (I) (FAS (I)) precluding a complex formation between NADPH and FAS (I)...

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Detalles Bibliográficos
Autores principales: Khani-Meinagh, Hossein, Mostafavi, Hossein, Reiling, Norbert, Mahdavi, Majid, Zarrini, Gholamreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879708/
https://www.ncbi.nlm.nih.gov/pubmed/31799156
http://dx.doi.org/10.15171/bi.2019.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879708/
https://www.ncbi.nlm.nih.gov/pubmed/31799156
http://dx.doi.org/10.15171/bi.2019.25

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