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Design, synthesis and evaluation of biological activities of some novel anti-TB agents with bio-reducible functional group

[Image: see text] Introduction: With regard to the anti-mycobacterial activity of 2-pyrazinoic acid esters (POEs), recent studies have shown that both pyrazine core and alkyl part of POE interact with the fatty acid synthase type (I) (FAS (I)) precluding a complex formation between NADPH and FAS (I)...

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Detalles Bibliográficos
Autores principales:	Khani-Meinagh, Hossein, Mostafavi, Hossein, Reiling, Norbert, Mahdavi, Majid, Zarrini, Gholamreza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tabriz University of Medical Sciences 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879708/ https://www.ncbi.nlm.nih.gov/pubmed/31799156 http://dx.doi.org/10.15171/bi.2019.25

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