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CD71(+) Erythroid Cells Exacerbate HIV-1 Susceptibility, Mediate trans-Infection, and Harbor Infective Viral Particles

CD71(+) erythroid cells (CECs) have a wide range of immunomodulatory properties. Here, we show that CECs are expanded in the peripheral blood of HIV patients, with a positive correlation between their frequency and the plasma viral load. CECs from HIV patients and human cord blood/placenta exacerbat...

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Detalles Bibliográficos
Autores principales: Namdar, Afshin, Dunsmore, Garett, Shahbaz, Shima, Koleva, Petya, Xu, Lai, Jovel, Juan, Houston, Stan, Elahi, Shokrollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879723/
https://www.ncbi.nlm.nih.gov/pubmed/31772057
http://dx.doi.org/10.1128/mBio.02767-19