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Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice

Host genetics plays an important role in determining the outcome of Mycobacterium tuberculosis infection. We previously found that Collaborative Cross (CC) mouse strains differ in their susceptibility to M. tuberculosis and that the CC042/GeniUnc (CC042) strain suffered from a rapidly progressive di...

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Detalles Bibliográficos
Autores principales: Smith, Clare M., Proulx, Megan K., Lai, Rocky, Kiritsy, Michael C., Bell, Timothy A., Hock, Pablo, Pardo-Manuel de Villena, Fernando, Ferris, Martin T., Baker, Richard E., Behar, Samuel M., Sassetti, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879725/
https://www.ncbi.nlm.nih.gov/pubmed/31772048
http://dx.doi.org/10.1128/mBio.02791-19