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Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E(2) synthesis in the brain and their behavioral relevance
Inflammation in the brain and periphery has been associated with stress-related pathology of mental illness. We have shown that prostaglandin (PG) E(2), an arachidonic acid-derived lipid mediator, and innate immune receptors Toll-like receptor (TLR) 2/4 are crucial for repeated stress-induced behavi...
Autores principales: | Nie, Xiang, Kitaoka, Shiho, Shinohara, Masakazu, Kakizuka, Akira, Narumiya, Shuh, Furuyashiki, Tomoyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879743/ https://www.ncbi.nlm.nih.gov/pubmed/31772309 http://dx.doi.org/10.1038/s41598-019-54082-5 |
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