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Lipid phosphatase SHIP‐1 regulates chondrocyte hypertrophy and skeletal development

SH2‐containing inositol‐5′‐phosphatase‐1 (SHIP‐1) controls the phosphatidylinositol‐3′‐kinase (PI3K) initiated signaling pathway by limiting cell membrane recruitment and activation of Akt. Despite the fact that many of the growth factors important to cartilage development and functions are able to...

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Detalles Bibliográficos
Autores principales: So, Eui‐Young, Sun, Changqi, Wu, Keith Q., Driesman, Adam, Leggett, Susan, Isaac, Mauricio, Spangler, Travis, Dubielecka‐Szczerba, Patrycja M., Reginato, Anthony M., Liang, Olin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879780/
https://www.ncbi.nlm.nih.gov/pubmed/31287165
http://dx.doi.org/10.1002/jcp.29063