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Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by interleukin-1 receptor antagonist IL-1Ra
The bacterium Mycobacterium tuberculosis (Mtb) causes tuberculosis (TB) and is responsible for more human mortality than any other single pathogen(1). Progression to active disease occurs in only a fraction of infected individuals and is predicted by an elevated type I interferon (IFN) response(2-7)...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879852/ https://www.ncbi.nlm.nih.gov/pubmed/31611644 http://dx.doi.org/10.1038/s41564-019-0578-3 |