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Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity
Posttraumatic stress disorder (PTSD) is associated with neuroendocrine alterations and metabolic abnormalities; however, how metabolism is affected by neuroendocrine disturbances is unclear. The data from combat-exposed veterans with PTSD show increased glycolysis to lactate flux, reduced TCA cycle...
Autores principales: | Somvanshi, Pramod R., Mellon, Synthia H., Flory, Janine D., Abu-Amara, Duna, Wolkowitz, Owen M., Yehuda, Rachel, Jett, Marti, Hood, Leroy, Marmar, Charles, Doyle, Francis J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879860/ https://www.ncbi.nlm.nih.gov/pubmed/31322414 http://dx.doi.org/10.1152/ajpendo.00065.2019 |
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