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Biomarker-guided trials: Challenges in practice

Biomarker-guided trials have drawn considerable attention as they promise to lead to improvements in the benefit-risk ratio of treatments and enhanced opportunities for drug development. A variety of such designs have been proposed in the literature, many of which have been adopted in practice. Impl...

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Detalles Bibliográficos
Autores principales: Antoniou, M., Kolamunnage-Dona, R., Wason, J., Bathia, R., Billingham, C., Bliss, J.M., Brown, L.C., Gillman, A., Paul, J., Jorgensen, A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879976/
https://www.ncbi.nlm.nih.gov/pubmed/31788574
http://dx.doi.org/10.1016/j.conctc.2019.100493