Isoniazid acetylation phenotypes in the Sudanese population; findings and implications

BACKGROUND: Isoniazid (INH) is the mainstay antimicrobial in the treatment of tuberculosis (TB). It is acetlylated in the liver to acetyl-INH. However, there is variation in rate of acetylation of INH among TB patients (i.e. fast, intermediate or slow acetylators) which impacts on the treatment outc...

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Detalles Bibliográficos
Autores principales: Ali, Monadil H., Alrasheedy, Alian A., Kibuule, Dan, Hassali, Mohamed Azmi, Godman, Brian, Abdelwahab, Mohammed F., Abbadi, Raef Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879993/
https://www.ncbi.nlm.nih.gov/pubmed/31788562
http://dx.doi.org/10.1016/j.jctube.2019.100120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879993/
https://www.ncbi.nlm.nih.gov/pubmed/31788562
http://dx.doi.org/10.1016/j.jctube.2019.100120

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