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Monitoring method for transgene expression in target tissue by blood sampling

In this study, we have developed a novel method to monitor transgene expression in tissues by blood sampling. We administered plasmid DNA (pDNA) encoding non-secretory form of firefly luciferase as a reporter gene and pDNA encoding secretable Gaussia princeps luciferase as a monitor gene simultaneou...

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Detalles Bibliográficos
Autores principales: Kinoshita, Eriko, Fumoto, Shintaro, Hori, Yuta, Yoshikawa, Naoki, Miyamoto, Hirotaka, Sasaki, Hitoshi, Nakamura, Junzo, Tanaka, Takashi, Nishida, Koyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880019/
https://www.ncbi.nlm.nih.gov/pubmed/31788440
http://dx.doi.org/10.1016/j.btre.2019.e00401