High-Affinity DARPin Allows Targeting of MeV to Glioblastoma Multiforme in Combination with Protease Targeting without Loss of Potency

Measles virus (MeV) is naturally cytolytic by extensive cell-to-cell fusion. Vaccine-derived MeV is toxic for cancer cells and is clinically tested as oncolytic virus. To combine the potential of MeV with enhanced safety, different targeting strategies have been described. We generated a receptor-ta...

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Detalles Bibliográficos
Autores principales: Hanauer, Jan R.H., Koch, Vivian, Lauer, Ulrich M., Mühlebach, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880102/
https://www.ncbi.nlm.nih.gov/pubmed/31788553
http://dx.doi.org/10.1016/j.omto.2019.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880102/
https://www.ncbi.nlm.nih.gov/pubmed/31788553
http://dx.doi.org/10.1016/j.omto.2019.10.004

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