Amorphous solid dispersion formation via solvent granulation – A case study with ritonavir and lopinavir

Herein, we evaluate the potential of using a simple solvent granulation process to prepare a binary drug amorphous solid dispersion (ASD) containing two anti-HIV drugs, ritonavir and lopinavir. The drugs were granulated onto a mixture of lactose and microcrystalline cellulose, followed by drying to...

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Detalles Bibliográficos
Autores principales: Trasi, Niraj S., Bhujbal, Sonal, Zhou, Qi Tony, Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880113/
https://www.ncbi.nlm.nih.gov/pubmed/31788669
http://dx.doi.org/10.1016/j.ijpx.2019.100035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880113/
https://www.ncbi.nlm.nih.gov/pubmed/31788669
http://dx.doi.org/10.1016/j.ijpx.2019.100035

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