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Amorphous solid dispersion formation via solvent granulation – A case study with ritonavir and lopinavir
Herein, we evaluate the potential of using a simple solvent granulation process to prepare a binary drug amorphous solid dispersion (ASD) containing two anti-HIV drugs, ritonavir and lopinavir. The drugs were granulated onto a mixture of lactose and microcrystalline cellulose, followed by drying to...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880113/ https://www.ncbi.nlm.nih.gov/pubmed/31788669 http://dx.doi.org/10.1016/j.ijpx.2019.100035 |