Foxo in T Cells Regulates Thermogenic Program through Ccr4/Ccl22 Axis

Crosstalk between immunity and the thermogenic program has provided insight into metabolic energy regulation. Here, we generated thermogenic program-accelerating mice (T-QKO), in which Foxo1 is knockout and Foxo3 is hetero-knockout in CD4(+) T cells. T-QKO exhibit lean phenotype under HFD due to inc...

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Detalles Bibliográficos
Autores principales: Kikuchi, Tetsuhiro, Nakae, Jun, Kawano, Yoshinaga, Watanabe, Nobuyuki, Onodera, Masafumi, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880116/
https://www.ncbi.nlm.nih.gov/pubmed/31756626
http://dx.doi.org/10.1016/j.isci.2019.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880116/
https://www.ncbi.nlm.nih.gov/pubmed/31756626
http://dx.doi.org/10.1016/j.isci.2019.11.006

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