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Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 Factor

When expressed in virus-producing cells, the cellular multipass transmembrane protein SERINC5 reduces the infectivity of HIV-1 particles and is counteracted by HIV-1 Nef. Due to the unavailability of an antibody of sufficient specificity and sensitivity, investigation of SERINC5 protein expression a...

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Detalles Bibliográficos
Autores principales: Passos, Vânia, Zillinger, Thomas, Casartelli, Nicoletta, Wachs, Amelie S., Xu, Shuting, Malassa, Angelina, Steppich, Katja, Schilling, Hildegard, Franz, Sergej, Todt, Daniel, Steinmann, Eike, Sutter, Kathrin, Dittmer, Ulf, Bohne, Jens, Schwartz, Olivier, Barchet, Winfried, Goffinet, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880170/
https://www.ncbi.nlm.nih.gov/pubmed/31597782
http://dx.doi.org/10.1128/JVI.01221-19