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Structure–Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives

Background: As a library of cannabinoid (CB) derivatives with (-)-trans-cannabidiol (CBD) or (-)-trans-cannabidivarin (CBDV) scaffold, we synthesized nine novel cannabinoids: 2-hydroxyethyl cannabidiolate (2-HEC), 2-hydroxypentyl cannabidiolate (2-HPC), 2,3-dihydroxypropyl cannabidiolate (GCBD), cyc...

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Detalles Bibliográficos
Autores principales: Götz, Marcus R., Collado, Juan A., Fernández-Ruiz, Javier, Fiebich, Bernd L., García-Toscano, Laura, Gómez-Cañas, María, Koch, Oskar, Leha, Andreas, Muñoz, Eduardo, Navarrete, Carmen, Pazos, Maria R., Holzgrabe, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880192/
https://www.ncbi.nlm.nih.gov/pubmed/31824305
http://dx.doi.org/10.3389/fphar.2019.01284