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Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

BACKGROUND: The “nonclassic” apparent mineralocorticoid excess (NC-AME) has been identified in approximately 7% of general population. This phenotype is characterized by low plasma renin activity (PRA), high serum cortisol (F) to cortisone (E) ratio, low cortisone, high Fractional Excretion of potas...

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Detalles Bibliográficos
Autores principales: Tapia-Castillo, Alejandra, Guanzon, Dominic, Palma, Carlos, Lai, Andrew, Barros, Eric, Allende, Fidel, Vecchiola, Andrea, Fardella, Carlos E., Salomón, Carlos, Carvajal, Cristian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880399/
https://www.ncbi.nlm.nih.gov/pubmed/31775784
http://dx.doi.org/10.1186/s12967-019-02143-8