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Phosphate regulator PhoP directly and indirectly controls transcription of the erythromycin biosynthesis genes in Saccharopolyspora erythraea

BACKGROUND: The choice of phosphate/nitrogen source and their concentrations have been shown to have great influences on antibiotic production. However, the underlying mechanisms responsible for this remain poorly understood. RESULTS: We show that nutrient-sensing regulator PhoP (phosphate regulator...

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Detalles Bibliográficos
Autores principales: Xu, Ya, You, Di, Yao, Li-li, Chu, Xiaohe, Ye, Bang-Ce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880422/
https://www.ncbi.nlm.nih.gov/pubmed/31775761
http://dx.doi.org/10.1186/s12934-019-1258-y