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The balance between mitotic death and mitotic slippage in acute leukemia: a new therapeutic window?

Mitosis is the process whereby an eukaryotic cell divides into two identical copies. Different multiprotein complexes are involved in the fine regulation of cell division, including the mitotic promoting factor and the anaphase promoting complex. Prolonged mitosis can result in cellular division, ce...

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Detalles Bibliográficos
Autores principales: Ghelli Luserna di Rorà, Andrea, Martinelli, Giovanni, Simonetti, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880427/
https://www.ncbi.nlm.nih.gov/pubmed/31771633
http://dx.doi.org/10.1186/s13045-019-0808-4