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Inhibiting miR-155 protects against myocardial ischemia/reperfusion injury via targeted regulation of HIF-1α in rats

OBJECTIVE(S): The aim of this study was to identify the role of miR-155 in the myocardial ischemia/reperfusion (I/R) injury through targeting hypoxia-inducible factor 1-alpha (HIF-1α). MATERIALS AND METHODS: We constructed rat models with myocardial I/R injury and H9C2 cell models with hypoxia/reoxy...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Guo, Xu, Xiao-Ming, Ji, Hui, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880526/
https://www.ncbi.nlm.nih.gov/pubmed/31807249
http://dx.doi.org/10.22038/ijbms.2019.34853.8270