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Inhibiting miR-155 protects against myocardial ischemia/reperfusion injury via targeted regulation of HIF-1α in rats
OBJECTIVE(S): The aim of this study was to identify the role of miR-155 in the myocardial ischemia/reperfusion (I/R) injury through targeting hypoxia-inducible factor 1-alpha (HIF-1α). MATERIALS AND METHODS: We constructed rat models with myocardial I/R injury and H9C2 cell models with hypoxia/reoxy...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mashhad University of Medical Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880526/ https://www.ncbi.nlm.nih.gov/pubmed/31807249 http://dx.doi.org/10.22038/ijbms.2019.34853.8270 |