Validation and characterisation of a DNA methylation alcohol biomarker across the life course

BACKGROUND: Recently, an alcohol predictor was developed using DNA methylation at 144 CpG sites (DNAm-Alc) as a biomarker for improved clinical or epidemiologic assessment of alcohol-related ill health. We validate the performance and characterise the drivers of this DNAm-Alc for the first time in i...

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Detalles Bibliográficos
Autores principales: Yousefi, Paul Darius, Richmond, Rebecca, Langdon, Ryan, Ness, Andrew, Liu, Chunyu, Levy, Daniel, Relton, Caroline, Suderman, Matthew, Zuccolo, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880546/
https://www.ncbi.nlm.nih.gov/pubmed/31775873
http://dx.doi.org/10.1186/s13148-019-0753-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880546/
https://www.ncbi.nlm.nih.gov/pubmed/31775873
http://dx.doi.org/10.1186/s13148-019-0753-7

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