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Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood

BACKGROUND: Late-onset Alzheimer’s disease (AD) is a complex multifactorial affliction, the pathogenesis of which is thought to involve gene-environment interactions that might be captured in the epigenome. The present study investigated epigenome-wide patterns of DNA methylation (5-methylcytosine,...

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Detalles Bibliográficos
Autores principales: Lardenoije, Roy, Roubroeks, Janou A. Y., Pishva, Ehsan, Leber, Markus, Wagner, Holger, Iatrou, Artemis, Smith, Adam R., Smith, Rebecca G., Eijssen, Lars M. T., Kleineidam, Luca, Kawalia, Amit, Hoffmann, Per, Luck, Tobias, Riedel-Heller, Steffi, Jessen, Frank, Maier, Wolfgang, Wagner, Michael, Hurlemann, René, Kenis, Gunter, Ali, Muhammad, del Sol, Antonio, Mastroeni, Diego, Delvaux, Elaine, Coleman, Paul D., Mill, Jonathan, Rutten, Bart P. F., Lunnon, Katie, Ramirez, Alfredo, van den Hove, Daniël L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880587/
https://www.ncbi.nlm.nih.gov/pubmed/31775875
http://dx.doi.org/10.1186/s13148-019-0755-5