Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors

We have examined the regulation of mutually exclusive Cav2.2 exon 37a and b variants by the mouse μ-opioid receptor (mMOR) C-terminal splice variants 1, 1C and 1O in tsA-201 cells. Electrophysiological analyses revealed that both channel isoforms exhibit DAMGO-induced voltage-dependent (Gβγ-mediated...

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Detalles Bibliográficos
Autores principales: Gandini, Maria A., Souza, Ivana A., Raval, Dvij, Xu, Jin, Pan, Ying-Xian, Zamponi, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880636/
https://www.ncbi.nlm.nih.gov/pubmed/31775826
http://dx.doi.org/10.1186/s13041-019-0524-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880636/
https://www.ncbi.nlm.nih.gov/pubmed/31775826
http://dx.doi.org/10.1186/s13041-019-0524-6

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