A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors

Alcohol produces both stimulant and sedative effects in humans and rodents. In humans, alcohol abuse disorder is associated with a higher stimulant and lower sedative responses to alcohol. Here, we show that this association is conserved in mice and demonstrate a causal link with another liability f...

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Detalles Bibliográficos
Autores principales: Bocarsly, Miriam E., da Silva e Silva, Daniel, Kolb, Vanessa, Luderman, Kathryn D., Shashikiran, Sannidhi, Rubinstein, Marcelo, Sibley, David R., Dobbs, Lauren K., Alvarez, Veronica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880649/
https://www.ncbi.nlm.nih.gov/pubmed/31665630
http://dx.doi.org/10.1016/j.celrep.2019.09.059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880649/
https://www.ncbi.nlm.nih.gov/pubmed/31665630
http://dx.doi.org/10.1016/j.celrep.2019.09.059

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