Palladium-catalyzed synthesis and nucleotide pyrophosphatase inhibition of benzo[4,5]furo[3,2-b]indoles

A two-step palladium-catalyzed procedure based on Suzuki–Miyaura cross coupling, followed by a double Buchwald–Hartwig reaction, allows for the synthesis of pharmaceutically relevant benzo[4,5]furo[3,2-b]indoles in moderate to very good yield. The synthesized compounds have been analyzed with regard...

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Detalles Bibliográficos
Autores principales: Do, Hoang Huy, Ullah, Saif, Villinger, Alexander, Lecka, Joanna, Sévigny, Jean, Ehlers, Peter, Iqbal, Jamshed, Langer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880817/
https://www.ncbi.nlm.nih.gov/pubmed/31807218
http://dx.doi.org/10.3762/bjoc.15.276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880817/
https://www.ncbi.nlm.nih.gov/pubmed/31807218
http://dx.doi.org/10.3762/bjoc.15.276

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