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miR-4666-3p and miR-329 Synergistically Suppress the Stemness of Colorectal Cancer Cells via Targeting TGF-β/Smad Pathway

Quiescent caner stem cells are identified as a subpopulation of colon cancer cells in dormant state and possess strong stem-cell like characteristics. Previously, we have identified this subpopulation in colorectal cancer (quiescent colon cancer stem cells, QCCSCs), and find QCCSCs are sensitive to...

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Detalles Bibliográficos
Autores principales: Ye, Jun, Lei, Jiacai, Fang, Qingqing, Shen, Yimin, Xia, Wenjie, Hu, Xiaoge, Xu, Qiuran, Yuan, Hongjun, Huang, Jian, Ni, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880832/
https://www.ncbi.nlm.nih.gov/pubmed/31824844
http://dx.doi.org/10.3389/fonc.2019.01251