A mechanism for how Cdr1/Nim1 kinase promotes mitotic entry by inhibiting Wee1

To enter into mitosis, cells must shut off the cell cycle inhibitor Wee1. SAD family protein kinases regulate Wee1 signaling in yeast and humans. In Schizosaccharomyces pombe, two SAD kinases (Cdr1/Nim1 and Cdr2) act as upstream inhibitors of Wee1. Previous studies found that S. pombe Cdr1/Nim1 dire...

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Detalles Bibliográficos
Autores principales: Opalko, Hannah E., Nasa, Isha, Kettenbach, Arminja N., Moseley, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880885/
https://www.ncbi.nlm.nih.gov/pubmed/31644361
http://dx.doi.org/10.1091/mbc.E19-08-0430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880885/
https://www.ncbi.nlm.nih.gov/pubmed/31644361
http://dx.doi.org/10.1091/mbc.E19-08-0430

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