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Influenza viruses that require 10 genomic segments as antiviral therapeutics
Influenza A viruses (IAVs) encode their genome across eight, negative sense RNA segments. During viral assembly, the failure to package all eight segments, or packaging a mutated segment, renders the resulting virion incompletely infectious. It is known that the accumulation of these defective parti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881065/ https://www.ncbi.nlm.nih.gov/pubmed/31730644 http://dx.doi.org/10.1371/journal.ppat.1008098 |