Gpr63 is a modifier of microcephaly in Ttc21b mouse mutants

The primary cilium is a signaling center critical for proper embryonic development. Previous studies have demonstrated that mice lacking Ttc21b have impaired retrograde trafficking within the cilium and multiple organogenesis phenotypes, including microcephaly. Interestingly, the severity of the mic...

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Detalles Bibliográficos
Autores principales: Snedeker, John, Gibbons, William J., Paulding, David F., Abdelhamed, Zakia, Prows, Daniel R., Stottmann, Rolf W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881074/
https://www.ncbi.nlm.nih.gov/pubmed/31730647
http://dx.doi.org/10.1371/journal.pgen.1008467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881074/
https://www.ncbi.nlm.nih.gov/pubmed/31730647
http://dx.doi.org/10.1371/journal.pgen.1008467

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