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An in silico analysis of robust but fragile gene regulation links enhancer length to robustness
Organisms must ensure that expression of genes is directed to the appropriate tissues at the correct times, while simultaneously ensuring that these gene regulatory systems are robust to perturbation. This idea is captured by a mathematical concept called r-robustness, which says that a system is ro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881076/ https://www.ncbi.nlm.nih.gov/pubmed/31730659 http://dx.doi.org/10.1371/journal.pcbi.1007497 |