Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen Pseudomonas aeruginosa

Evolution is at the core of the impending antibiotic crisis. Sustainable therapy must thus account for the adaptive potential of pathogens. One option is to exploit evolutionary trade-offs, like collateral sensitivity, where evolved resistance to one antibiotic causes hypersensitivity to another one...

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Detalles Bibliográficos
Autores principales: Barbosa, Camilo, Römhild, Roderich, Rosenstiel, Philip, Schulenburg, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881144/
https://www.ncbi.nlm.nih.gov/pubmed/31658946
http://dx.doi.org/10.7554/eLife.51481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881144/
https://www.ncbi.nlm.nih.gov/pubmed/31658946
http://dx.doi.org/10.7554/eLife.51481

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