Cargando…

Mechanistic reconstruction of glycoprotein secretion through monitoring of intracellular N-glycan processing

N-linked glycosylation plays a fundamental role in determining the thermodynamic stability of proteins and is involved in multiple key biological processes. The mechanistic understanding of the intracellular machinery responsible for the stepwise biosynthesis of N-glycans is still incomplete due to...

Descripción completa

Detalles Bibliográficos
Autores principales: Arigoni-Affolter, Ilaria, Scibona, Ernesto, Lin, Chia-Wei, Brühlmann, David, Souquet, Jonathan, Broly, Hervé, Aebi, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881162/
https://www.ncbi.nlm.nih.gov/pubmed/31807707
http://dx.doi.org/10.1126/sciadv.aax8930