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Mechanistic reconstruction of glycoprotein secretion through monitoring of intracellular N-glycan processing
N-linked glycosylation plays a fundamental role in determining the thermodynamic stability of proteins and is involved in multiple key biological processes. The mechanistic understanding of the intracellular machinery responsible for the stepwise biosynthesis of N-glycans is still incomplete due to...
Autores principales: | Arigoni-Affolter, Ilaria, Scibona, Ernesto, Lin, Chia-Wei, Brühlmann, David, Souquet, Jonathan, Broly, Hervé, Aebi, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881162/ https://www.ncbi.nlm.nih.gov/pubmed/31807707 http://dx.doi.org/10.1126/sciadv.aax8930 |
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