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In vivo–mimicking microfluidic perfusion culture of pancreatic islet spheroids

Native pancreatic islets interact with neighboring cells by establishing three-dimensional (3D) structures, and are surrounded by perfusion at an interstitial flow level. However, flow effects are generally ignored in islet culture models, although cell perfusion is known to improve the cell microen...

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Detalles Bibliográficos
Autores principales: Jun, Yesl, Lee, JaeSeo, Choi, Seongkyun, Yang, Ji Hun, Sander, Maike, Chung, Seok, Lee, Sang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881167/
https://www.ncbi.nlm.nih.gov/pubmed/31807701
http://dx.doi.org/10.1126/sciadv.aax4520