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In vivo–mimicking microfluidic perfusion culture of pancreatic islet spheroids
Native pancreatic islets interact with neighboring cells by establishing three-dimensional (3D) structures, and are surrounded by perfusion at an interstitial flow level. However, flow effects are generally ignored in islet culture models, although cell perfusion is known to improve the cell microen...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881167/ https://www.ncbi.nlm.nih.gov/pubmed/31807701 http://dx.doi.org/10.1126/sciadv.aax4520 |