A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules

Sister chromatid cohesion requires cohesin to act as a protein linker to hold chromatids together. How cohesin tethers chromatids remains poorly understood. We have used optical tweezers to visualize cohesin as it holds DNA molecules. We show that cohesin complexes tether DNAs in the presence of Scc...

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Detalles Bibliográficos
Autores principales: Gutierrez-Escribano, Pilar, Newton, Matthew D., Llauró, Aida, Huber, Jonas, Tanasie, Loredana, Davy, Joseph, Aly, Isabel, Aramayo, Ricardo, Montoya, Alex, Kramer, Holger, Stigler, Johannes, Rueda, David S., Aragon, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881171/
https://www.ncbi.nlm.nih.gov/pubmed/31807710
http://dx.doi.org/10.1126/sciadv.aay6804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881171/
https://www.ncbi.nlm.nih.gov/pubmed/31807710
http://dx.doi.org/10.1126/sciadv.aay6804

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