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Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion

To maintain prolonged infection of mammals, African trypanosomes have evolved remarkable surface coats and a system of antigenic variation(1). Within these coats are receptors for macromolecular nutrients such as transferrin(2,3). These must be accessible to their ligands but must not confer suscept...

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Detalles Bibliográficos
Autores principales: Trevor, Camilla E., Gonzalez-Munoz, Andrea L., Macleod, Olivia J. S., Woodcock, Peter G., Rust, Steven, Vaughan, Tristan J., Garman, Elspeth F., Minter, Ralph, Carrington, Mark, Higgins, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881179/
https://www.ncbi.nlm.nih.gov/pubmed/31636418
http://dx.doi.org/10.1038/s41564-019-0589-0