Cargando…
Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion
To maintain prolonged infection of mammals, African trypanosomes have evolved remarkable surface coats and a system of antigenic variation(1). Within these coats are receptors for macromolecular nutrients such as transferrin(2,3). These must be accessible to their ligands but must not confer suscept...
Autores principales: | Trevor, Camilla E., Gonzalez-Munoz, Andrea L., Macleod, Olivia J. S., Woodcock, Peter G., Rust, Steven, Vaughan, Tristan J., Garman, Elspeth F., Minter, Ralph, Carrington, Mark, Higgins, Matthew K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881179/ https://www.ncbi.nlm.nih.gov/pubmed/31636418 http://dx.doi.org/10.1038/s41564-019-0589-0 |
Ejemplares similares
-
A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies
por: Macleod, Olivia J. S., et al.
Publicado: (2020) -
A transferrin receptor’s guide to African trypanosomes
por: Urbaniak, Michael D., et al.
Publicado: (2023) -
The Trypanosomal Transferrin Receptor of Trypanosoma Brucei—A Review
por: Kariuki, Christopher K., et al.
Publicado: (2019) -
Structural basis for ligand and innate immunity factor uptake by the
trypanosome haptoglobin-haemoglobin receptor
por: Lane-Serff, Harriet, et al.
Publicado: (2014) -
Mechanism for Multiple Ligand Recognition by the Human Transferrin Receptor
por: Giannetti, Anthony M, et al.
Publicado: (2003)