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Elucidation of a unique sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut

Sialic acid (Neu5Ac) is commonly found in terminal location of colonic mucins glycans where it is a much-coveted nutrient for gut bacteria including Ruminococcus gnavus. R. gnavus is part of the healthy gut microbiota in humans but shows a disproportionate representation in diseases. There is theref...

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Detalles Bibliográficos
Autores principales: Bell, Andrew, Brunt, Jason, Crost, Emmanuelle, Vaux, Laura, Nepravishta, Ridvan, Owen, C. David, Latousakis, Dimitrios, Xiao, An, Li, Wanqing, Chen, Xi, Walsh, Martin A., Claesen, Jan, Angulo, Jesus, Thomas, Gavin H., Juge, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881182/
https://www.ncbi.nlm.nih.gov/pubmed/31636419
http://dx.doi.org/10.1038/s41564-019-0590-7