A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood

The pathology of sickle cell disease begins with the polymerization of intracellular hemoglobin under low oxygen tension, which leads to increased blood effective viscosity and vaso-occlusion. However, it has remained unclear how single-cell changes propagate up to the scale of bulk blood effective...

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Detalles Bibliográficos
Autores principales: Valdez, José M., Datta, Yvonne H., Higgins, John M., Wood, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881198/
https://www.ncbi.nlm.nih.gov/pubmed/31803859
http://dx.doi.org/10.1063/1.5118212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881198/
https://www.ncbi.nlm.nih.gov/pubmed/31803859
http://dx.doi.org/10.1063/1.5118212

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