Binding of von Willebrand Factor to Complement C1q Decreases the Phagocytosis of Cholesterol Crystals and Subsequent IL-1 Secretion in Macrophages

Complement C1q, the initiation molecule of the classical pathway, exerts various immunomodulatory functions independent of complement activation. Non-classical functions of C1q include the clearance of apoptotic cells and cholesterol crystals (CC), as well as the modulation of cytokine secretion by...

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Detalles Bibliográficos
Autores principales: Donat, Claudia, Thanei, Sophia, Trendelenburg, Marten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881245/
https://www.ncbi.nlm.nih.gov/pubmed/31824501
http://dx.doi.org/10.3389/fimmu.2019.02712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881245/
https://www.ncbi.nlm.nih.gov/pubmed/31824501
http://dx.doi.org/10.3389/fimmu.2019.02712

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