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YKL-40/CHI3L1 facilitates migration and invasion in HER2 overexpressing breast epithelial progenitor cells and generates a niche for capillary-like network formation

Epithelial to mesenchymal transition (EMT) is a developmental event that is hijacked in some diseases such as fibrosis and cancer. In cancer, EMT has been linked to increased invasion and metastasis and is generally associated with a poor prognosis. In this study, we have compared phenotypic and fun...

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Detalles Bibliográficos
Autores principales: Morera, Erika, Steinhäuser, Sarah Sophie, Budkova, Zuzana, Ingthorsson, Saevar, Kricker, Jennifer, Krueger, Aileen, Traustadottir, Gunnhildur Asta, Gudjonsson, Thorarinn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881255/
https://www.ncbi.nlm.nih.gov/pubmed/31482369
http://dx.doi.org/10.1007/s11626-019-00403-x