A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

Glycosylation plays important roles in cellular function and endows protein therapeutics with beneficial properties. However, constructing biosynthetic pathways to study and engineer precise glycan structures on proteins remains a bottleneck. Here, we report a modular, versatile cell-free platform f...

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Detalles Bibliográficos
Autores principales: Kightlinger, Weston, Duncker, Katherine E., Ramesh, Ashvita, Thames, Ariel H., Natarajan, Aravind, Stark, Jessica C., Yang, Allen, Lin, Liang, Mrksich, Milan, DeLisa, Matthew P., Jewett, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881289/
https://www.ncbi.nlm.nih.gov/pubmed/31776339
http://dx.doi.org/10.1038/s41467-019-12024-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881289/
https://www.ncbi.nlm.nih.gov/pubmed/31776339
http://dx.doi.org/10.1038/s41467-019-12024-9

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