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A cell-free biosynthesis platform for modular construction of protein glycosylation pathways
Glycosylation plays important roles in cellular function and endows protein therapeutics with beneficial properties. However, constructing biosynthetic pathways to study and engineer precise glycan structures on proteins remains a bottleneck. Here, we report a modular, versatile cell-free platform f...
Autores principales: | Kightlinger, Weston, Duncker, Katherine E., Ramesh, Ashvita, Thames, Ariel H., Natarajan, Aravind, Stark, Jessica C., Yang, Allen, Lin, Liang, Mrksich, Milan, DeLisa, Matthew P., Jewett, Michael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881289/ https://www.ncbi.nlm.nih.gov/pubmed/31776339 http://dx.doi.org/10.1038/s41467-019-12024-9 |
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