Seeding Activity-Based Detection Uncovers the Different Release Mechanisms of Seed-Competent Tau Versus Inert Tau via Lysosomal Exocytosis

The pathological aggregation of tau characterizes a set of neurodegenerative diseases collectively referred to as tauopathies. Recent studies using cellular and animal models have suggested that tau pathology progresses by trans-cellular propagation. The process of propagation is mediated by certain...

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Detalles Bibliográficos
Autores principales: Tanaka, Yuki, Yamada, Kaoru, Satake, Kyoko, Nishida, Itaru, Heuberger, Matthias, Kuwahara, Tomoki, Iwatsubo, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881304/
https://www.ncbi.nlm.nih.gov/pubmed/31824253
http://dx.doi.org/10.3389/fnins.2019.01258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881304/
https://www.ncbi.nlm.nih.gov/pubmed/31824253
http://dx.doi.org/10.3389/fnins.2019.01258

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