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Quantification of phosphoinositides reveals strong enrichment of PIP(2) in HIV-1 compared to producer cell membranes

Human immunodeficiency virus type 1 (HIV-1) acquires its lipid envelope during budding from the plasma membrane of the host cell. Various studies indicated that HIV-1 membranes differ from producer cell plasma membranes, suggesting budding from specialized membrane microdomains. The phosphoinositide...

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Detalles Bibliográficos
Autores principales: Mücksch, Frauke, Citir, Mevlut, Lüchtenborg, Christian, Glass, Bärbel, Traynor-Kaplan, Alexis, Schultz, Carsten, Brügger, Britta, Kräusslich, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881329/
https://www.ncbi.nlm.nih.gov/pubmed/31776383
http://dx.doi.org/10.1038/s41598-019-53939-z