Redox activation of JNK2α2 mediates thyroid hormone-stimulated proliferation of neonatal murine cardiomyocytes

Mitochondria-generated reactive oxygen species (mROS) are frequently associated with DNA damage and cell cycle arrest, but physiological increases in mROS serve to regulate specific cell functions. T3 is a major regulator of mROS, including hydrogen peroxide (H(2)O(2)). Here we show that exogenous t...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Lin, Bogush, Nikolay, Naib, Hussain, Perry, Jennifer, Calvert, John W., Martin, David I. K., Graham, Robert M., Naqvi, Nawazish, Husain, Ahsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881338/
https://www.ncbi.nlm.nih.gov/pubmed/31776360
http://dx.doi.org/10.1038/s41598-019-53705-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881338/
https://www.ncbi.nlm.nih.gov/pubmed/31776360
http://dx.doi.org/10.1038/s41598-019-53705-1

Ejemplares similares