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Redox activation of JNK2α2 mediates thyroid hormone-stimulated proliferation of neonatal murine cardiomyocytes
Mitochondria-generated reactive oxygen species (mROS) are frequently associated with DNA damage and cell cycle arrest, but physiological increases in mROS serve to regulate specific cell functions. T3 is a major regulator of mROS, including hydrogen peroxide (H(2)O(2)). Here we show that exogenous t...
Autores principales: | Tan, Lin, Bogush, Nikolay, Naib, Hussain, Perry, Jennifer, Calvert, John W., Martin, David I. K., Graham, Robert M., Naqvi, Nawazish, Husain, Ahsan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881338/ https://www.ncbi.nlm.nih.gov/pubmed/31776360 http://dx.doi.org/10.1038/s41598-019-53705-1 |
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