Direct visualization of human myosin II force generation using DNA origami-based thick filaments

The sarcomere, the minimal mechanical unit of muscle, is composed of myosins, which self-assemble into thick filaments that interact with actin-based thin filaments in a highly-structured lattice. This complex imposes a geometric restriction on myosin in force generation. However, how single myosins...

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Detalles Bibliográficos
Autores principales: Fujita, Keisuke, Ohmachi, Masashi, Ikezaki, Keigo, Yanagida, Toshio, Iwaki, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881340/
https://www.ncbi.nlm.nih.gov/pubmed/31799438
http://dx.doi.org/10.1038/s42003-019-0683-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881340/
https://www.ncbi.nlm.nih.gov/pubmed/31799438
http://dx.doi.org/10.1038/s42003-019-0683-0

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